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KMID : 0861020040190010041
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Korea Journal of Herbology
2004 Volume.19 No. 1 p.41 ~ p.46
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Effect of Oriental herb medicines on Serum Glucose and Lipid Concentration in Streptozotocin-induced Diabetic Rats
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Abstract
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Objectives: To examine the effect of Oriental herb medicines on serum glucose and lipid
concentration in streptozotocin-induced diabetic rats. For this study, the materials concerned with the useful Oriental herb medicines for Diabetes MellitudDM) were collected at the clinic of Daegu Haany University.
Methods: To verify the effects of Oriental herb medicines on serum glucose through streptozotocin-induced diabetic rats, some rats were injected 1 time with 50 mghg streptombcin intraperitoneally(1.P.) to induce diabetes, and other rats were injected with buffer I.P. as control group.
Results: The concentration of serum glucose in SZ(streptozotocin) plus Oriental herb medicines extract group was significant decrease than SZ(streptozotocin) control group(p<0.05). The concentration of cholesterol in SZ(streptozotocin) plus Oriental herb medicines extract group did not shown significant decrease than SZ(streptozotocin) control group(p<0.05). Also the concentration of triglycende in SZ(streptozotocin) plus Oriental herb medicines extract group did not shown significant decrease than SZ(streptozotocin) control group(p<0.05).
Conclusion: These results suggest that Oriental herb medicines extract used in this experimental could be applied to the treatment of diabetes mellitus.
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